Accuracy of prenatal diagnosis of congenital heart defects by fetal echocardiography:a 7-year experience in a Chinese tertiary obstetric center
10.3760/cma.j.issn.0253-3758.2009.04.013
- VernacularTitle:胎儿超声心动图产前诊断先天性心脏病准确性评价
- Author:
Ruo-Yan ZHU
1
;
Li-Chan LI
;
Rui-Yu CHEN
;
Li-Ye SHI
;
Jian-Mei NIU
;
Xiao WANG
;
Jin-Jin WANG
Author Information
1. 上海交通大学医学院附属国际和平妇幼保健院
- Keywords:
Ultrasonography,prenatal;
Heart defects,congenital
- From:
Chinese Journal of Cardiology
2009;37(4):343-346
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the prenatal diagnostic accuracy of fetal echocardiography for congenital heart defects.Methods Fetal echocardiographic databases from 2001 to 2007 were searched for patients with a prenatal diagnosis of congenital heart defect,medical records were obtained and the prenatal echocardiographic findings were correlated with postnatal echocardiography results or autopsy findings,if the pregnancy was terminated or the fetus died in utero.Results Prenatal diagnosis of congenital heart defects was made in 113 pregnancies at a mean gestational age of 26.8 weeks.Pathology or postnatal echocardiography was available in 79 cases(70%)and the accuracy of prenatal diagnosis was 86%(68/79).Prenatal diagnosis was accurate in 24 of 31 patients(77%)with conotruncal malformations,26 of 27 patients(96%)with septal defects,9 of 10 patients(90%)with valve abnormalities,and 5 of 6 patients(83%)with univentricular hearts.There were 4 false-positives and the positive predictive value was 95%(75/79).Conclusion Fetal echocardiography is a reliable tool for prenatal diagnosis of congenital heart defects despite Limitations for correctly diagnosing some spocific fetal heart defects.