Quantitative coronary angiography and intravascular ultrasound assessments on target lesion and reference vessel in patients with diabetes mellitus
10.3760/cma.j.issn.0253-3758.2009.08.011
- VernacularTitle:定量冠状动脉造影对糖尿病患者靶病变及参考血管的评价
- Author:
Ze-Ning JIN
1
;
Shu-Zheng L(U)
;
Yun-Dai CHEN
;
Fei YUAN
;
Xian-Tao SONG
;
Xiao-Fan WU
;
Li-Jie ZHANG
;
Fang REN
;
Chang-Jiang GE
;
Guo-Zhong WANG
;
Xue-Wei XU
Author Information
1. 首都医科大学附属北京安贞医院
- Keywords:
Coronary disease;
Diabetes mellitus;
Coronary angiography;
Ultrasound,interventional
- From:
Chinese Journal of Cardiology
2009;37(8):721-724
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the accuracy of quantitative coronary angiography ( QCA ) assessment on target lesion and reference vessel in patients with diabetes mellitus with intravascular ultrasound (IVUS) measurements as golden standard. Methods QCA and IVUS were performed in 52 diabetes mellitus patients [35 males, mean age (62.3 ±7. 1)years]. Regression equation was ascertained with the IVUS derived plaque burden as dependent and QCA derived vessel stenosis as independent variable. The measurement results derived from the two modalities on proximal and distal reference vessels were compared. Result The regression equation (constant = 0. 8286, P = 0. 001) of plaque burden and vessel stenosis derived from two modalities were significantly correlated ( r = 0. 691, P < 0. 001 ) but QCA overestimated the stenosis severity (57. 9% ± 15. 5% vs. 53. 5% ± 12. 9% , P <0. 01 ). Target vessels negative remodeling index in these patient was 0. 87 ±0.23. QCA significantly underestimated the proximal and distal reference segments vessel diameters [ ( 0. 81 ± 0. 24 ) mm, ( 0. 64 ± 0. 17 ) mm, all P < 0. 05 ] as compared to IVUS results. Conclusion Due to the significant negative vessel remodeling, QCA overestimated the stenosis severity and underestimated the reference segments vessel diameters in patients with diabetes mellitus.
