Progress in research on the anti-tumor effect of artesunate.
10.1007/s11655-008-0312-0
- Author:
Rong-rong HE
1
;
Huai-jun ZHOU
Author Information
1. Gulou Medical College of Integrative Chinese and Western Medicine, The No.1 Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing (210029), China.
- Publication Type:Journal Article
- MeSH:
Amebicides;
pharmacology;
Animals;
Antimalarials;
pharmacology;
Antineoplastic Agents;
pharmacology;
Apoptosis;
drug effects;
Artemisinins;
pharmacology;
Free Radicals;
metabolism;
Humans;
Immunosuppression;
Iron;
pharmacology;
Neovascularization, Pathologic;
drug therapy;
Tumor Cells, Cultured;
drug effects
- From:
Chinese journal of integrative medicine
2008;14(4):312-316
- CountryChina
- Language:English
-
Abstract:
It has been found in recent years that Artesunate (Art), a water soluble derivative of arteannuin, mainly previously used for its anti-malarial activity, has some other effects, e.g. it could act as an anti-tumor agent by way of inducing cell apoptosis, antagonizing angiogenesis, reversing immunosuppression of tumor cells, etc. More and more attention is being paid to the anti-tumor effects of Art. Such progress is reviewed in this paper.
