Clinical observation on the treatment of male neoplastic anemia with Yixuesheng capsule combined with recombination human erythropoietin.
- Author:
Zhi CHENG
1
;
Jia-Li WU
;
Jun-Fa CHEN
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Anemia; blood; complications; drug therapy; Capsules; Drug Therapy, Combination; Drugs, Chinese Herbal; pharmacology; therapeutic use; Erythrocytes; drug effects; Erythropoietin; pharmacology; therapeutic use; Gonadal Steroid Hormones; blood; Hematocrit; Hemoglobins; metabolism; Humans; Male; Middle Aged; Neoplasms; blood; complications; drug therapy; Recombinant Proteins; Treatment Outcome
- From: Chinese journal of integrative medicine 2009;15(1):63-65
- CountryChina
- Language:English
-
Abstract:
OBJECTIVETo explore the efficacy and mechanism of Yixuesheng capsule (, YXS) combined with recombination human erythropoietin (RHE) in treating male neoplastic anemia (NA).
METHODSSixty-five patients were randomized into two groups, the 33 patients in the treated group treated with a combined therapy of YXS and RHE, and the 32 in the control group treated with RHE alone, all for 12 weeks. Related clinical indexes, including hemoglobin (Hgb), red blood cell (RBC), hematocrit (HMC), testosterone (T), estradiol (E(2)) and prolactin (PRL), were measured before and after treatment.)
RESULTSAfter treatment, Hgb in the treated group and the control group was 108+/-5 g/L and 104+/-8 g/L respectively, showing marked improvement as compared with that before treatment (P<0.01), and the improvement in the former was more significant than that in the latter (P<0.05). Further, the level of T was also increased in the treated group after treatment (P<0.05), and showed a significant difference from that of the control group (P<0.05).
CONCLUSIONSYXS capsule combined with RHE shows a better therapeutic effect in treating NA than that of RHE alone, and the effect might be through stimulation by YXS of erythropoiesis which could promote the secretion of testosterone.
