Analysis and exploration on adverse reactions of four kinds of andrographolide injections.

Author: Dong XIANG ¹ ; Meng-Die WANG ¹ ; Wen-Qing WANG ¹ ; Chun-Yang SHI ¹ ; Xue-Jia XIE ¹ ; Jian-Guo FANG ¹
Author Information

1. Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Publication Type:Journal Article
Keywords: adverse reactions; andrographolide; safety study; traditional Chinese medicine injections
From: China Journal of Chinese Materia Medica 2016;41(12):2350-2355
CountryChina
Language:Chinese
Abstract: Concerned literature on four kinds of andrographolide injections in recent 15 years were searched in CNKI, Wanfang and VIP databases. The adverse drug reaction(ADR) cases of Chuanhuning, Yanhuning, Xiyanping and Lianbizhi injections were classified and analyzed statistically, including a total of 194 articles and 3 479 cases. The ADR clinical characteristics and occurrence regularity of these four andrographolide injections were analyzed and compared from the gender, age, primary disease, emergence time of ADR, clinical manifestation, allergy history, dosage, prognosis and combined medication of the patients. It is useful to provide valuable references for rational use of these andrographolide injections in clinical practice.