Association between fasting and postprandial triglyceride levels and carotid intima-media thickness in type 2 diabetes patients.
- Author:
Xiang CHEN
1
;
Haoming TIAN
;
Rui LIU
Author Information
- Publication Type:Journal Article
- MeSH: Carotid Arteries; diagnostic imaging; Diabetes Mellitus, Type 2; blood; diagnostic imaging; Eating; Female; Humans; Male; Middle Aged; Risk Factors; Triglycerides; blood; Tunica Intima; diagnostic imaging; Tunica Media; diagnostic imaging; Ultrasonography
- From: Chinese Medical Journal 2003;116(12):1933-1935
- CountryChina
- Language:English
-
Abstract:
OBJECTIVETo investigate the association of fasting and postpiandial triglyceride with carotid intima-media thickness among type 2 diabetic patients in southeast China.
METHODSA total of 78 type 2 diabetic patients from southeast China were recruited. All the subjects underwent a standardized mixed-meal test (SMMT) and an oral glucose tolerance test. Carotid intima-media thickness (IMT) was measured by color doppler ultrasound examination.
RESULTSPostprandial triglyceride (PTG) after SMMT increased significantly in type 2 diabetic patients. The carotid IMT in patients with postprandial hypertriglyceridemia was significantly greater than that in patients with postprandial normal-triglyceridemia (0.90 mm vs 0.81 mm, P < 0.05), which remained significant after adjustment for fasting TG and HDL-c levels, and the IMT in patients with fasting hypertriglyceridemia only had tendency to increase compared to patients with fasting normal-triglyceridemia (0.87 mm vs 0.84 mm, P > 0.05).
CONCLUSIONThe results suggest that postprandial hypertriglyceridemia may be an independent risk factor of early atherosclerosis in type 2 diabetes.
