Topical melagenine for repigmentation in twenty-two child patients with vitiligo on the scalp.
- Author:
Ai-e XU
1
;
Xiao-dong WEI
Author Information
- Publication Type:Journal Article
- MeSH: Administration, Topical; Adolescent; Child; Child, Preschool; Female; Humans; Infrared Rays; therapeutic use; Lipoproteins; administration & dosage; Male; Scalp Dermatoses; drug therapy; Vitiligo; drug therapy
- From: Chinese Medical Journal 2004;117(2):199-201
- CountryChina
- Language:English
-
Abstract:
BACKGROUNDThe purpose of this study was to evaluate the efficacy of topical melagenine for repigmentation in child patients with vitiligo on the scalp.
METHODSTwenty-two child patients with vitiligo on the scalp were treated with 1.2 mg/ml aqueous melagenine in combination with 20 minutes of infrared exposure twice daily.
RESULTSIn 4 patients (18.2%), melagenine treatment in combination with infrared exposure led to complete recovery; in 6 patients (27.3%), treatment was shown to be effective; in 8 patients (36.3%), treatment led to improvements in patient condition; and only 4 patients (18.2%) showed no response after 1 - 2 treatment sessions. The general effective rate of melagenine-infrared combination treatment was 45.5% for the children with vitiligo on the scalp, and treatment was accompanied by minimal side effects.
CONCLUSIONMelagenine may be efficacious and a safe treatment option for childhood vitiligo affecting the scalp.
