Phenolic constituents from Lysimachia patungensis.
- Author:
Peng ZENG
1
;
Yong ZHANG
;
Chen PAN
;
Qi JIA
;
Fu-Jiang GUO
;
Wei-Liang ZHU
;
Yi-Ming LI
;
Kai-Xian CHEN
Author Information
1. School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
- Publication Type:Journal Article
- MeSH:
Chalcones;
chemistry;
isolation & purification;
Cinnamates;
chemistry;
isolation & purification;
Molecular Structure;
Phenols;
chemistry;
isolation & purification;
Plants, Medicinal;
chemistry;
Primulaceae;
chemistry;
Quercetin;
analogs & derivatives;
chemistry;
isolation & purification;
Rutin;
chemistry;
isolation & purification
- From:
Acta Pharmaceutica Sinica
2013;48(3):377-382
- CountryChina
- Language:Chinese
-
Abstract:
To study the chemical constituents of Lysimachia patungensis Hand.-Mazz., silica gel column chromatography, reverse phase ODS column chromatography, MCI and Sephadex LH-20, were used to separate the 95% EtOH extract of the whole plant of Lysimachia patungensis Hand.-Mazz.. The structures of the isolated compounds have been established on the basis of chemical and NMR spectroscopic evidence as well as ESI-MS in some cases. Twelve phenolic compounds were obtained and identified as quercetin-3, 3'-di- O-alpha-L-rhamnoside (1), myricetrin (2), quercitrin (3), rutin (4), 2-hydroxynaringenin-4'-O-glucopyranoside (5), naringenin 7-O-glucopyranoside (6), liquiritin apioside (7), licochalcone B (8), tetrahydroxymethoxy chalcone (9), methyl-p-coumarate (10), 2, 4, 6-trihydroxy acetophenone-2-O-glucopyranoside (11) and vaccihein A (12). Among them, compound 1 is a new compound, and compounds 5, 11 and 12 are isolated from the genus Lysimachia L. for the first time, and the others are isolated from the plant for the first time.
