Progress in the study of targeted drug delivery systems for cancer stem cells.
- Author:
Ming-Xi QIAO
1
;
Xiao-Jun ZHANG
;
B A SHUANG
;
Hai-Yang HU
;
Xiu-Li ZHAO
;
Da-Wei CHEN
Author Information
1. School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Antineoplastic Agents;
pharmacology;
therapeutic use;
Apoptosis;
drug effects;
Drug Delivery Systems;
methods;
Drug Resistance, Neoplasm;
Flow Cytometry;
Humans;
Neoplasms;
drug therapy;
pathology;
Neoplastic Stem Cells;
drug effects;
pathology;
Signal Transduction;
drug effects;
Wnt Signaling Pathway;
drug effects
- From:
Acta Pharmaceutica Sinica
2013;48(4):477-483
- CountryChina
- Language:Chinese
-
Abstract:
The discovery, sorting and identification methods as well as targeted drug delivery systems for cancer stem cells (CSCs) have been reviewed by consulting the recent research papers. CSCs have been believed to be responsible for the occurrence and development of chemo-resistance, leading to the failure of chemotherapy. Much progress has been made in the approaches for CSCs targeting drug delivery systems. The understanding and targeted drug delivery systems for CSCs are promising to provide an alternative for cancer therapy.
