Chemical constituents from the linseed meal.
- Author:
Li SONG
1
;
Jian-Gong SHI
;
Sheng LIN
;
Yong-Chun YANG
;
Chun-Suo YAO
Author Information
1. Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
- Publication Type:Journal Article
- MeSH:
Amygdalin;
analogs & derivatives;
chemistry;
isolation & purification;
Deoxyadenosines;
chemistry;
isolation & purification;
Deoxyguanosine;
chemistry;
isolation & purification;
Flax;
chemistry;
Glucosides;
chemistry;
isolation & purification;
Glycosides;
chemistry;
isolation & purification;
Lignans;
chemistry;
isolation & purification;
Molecular Structure;
Nitriles;
chemistry;
isolation & purification;
Plants, Medicinal;
chemistry;
Seeds;
chemistry
- From:
Acta Pharmaceutica Sinica
2013;48(4):521-525
- CountryChina
- Language:Chinese
-
Abstract:
Ten compounds were isolated from the 70% ethanol extract of linseed meal (Linum usitatissimum L) through a combination of various chromatographic techniques, including silica gel, macroporous adsorbent resin, Sephadex LH-20, and preparative HPLC. On the basis of spectroscopic data analysis, they were elucidated as 1-methylethyl-2-O-beta-D-glucopyranosyl-(1" --> 6')-beta-D-glucopyanoside (1), linustatin (2), neolinustatin (3), lotaustralin (4), linamarin (5), deoxyguanosine (6), deoxyadenosine (7), (+)-pinoresinol-4'-O-beta-D-glucopyranoside (8), 4-O-beta-D-glucopyranosylvanillyl alcohol (9) and tachioside (10), separately. Among them, compound 1 is a new compound, and compounds 6, 8 and 10 were isolated from the linseed meal for the first time.
