Separation and purification processes of alkaloids from Lotus plumule with macroporous adsorption resin.
- Author:
Shao LIU
1
;
Peng LEI
;
Xin-Zhong LI
;
Ying-Hua CHEN
Author Information
- Publication Type:Journal Article
- MeSH: Adsorption; Benzylisoquinolines; isolation & purification; Drugs, Chinese Herbal; isolation & purification; Nelumbo; chemistry; Plants, Medicinal; chemistry; Resins, Synthetic; chemistry; Seeds; chemistry; Technology, Pharmaceutical; methods
- From: China Journal of Chinese Materia Medica 2007;32(10):912-915
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the optimal separation of the alkaloids from Lotus plumule by selecting appropriate macroporous adsorption resins.
METHODTo evaluated the separating efficiency by measuring the adsorption ratio, eluting ratio and the concentration of neferine.
RESULTThe LSA -5B macroporous adsorption resin prolided the optimal separating efficiency. The best adsorption capacity was achieved with the following conditions: the concentration of extact liquid was 0. 125 g x mL(-1) (equivalence to raw material), then the resin was washed by water to remove impurity and alkaloids were desorbed by 50% ethanol.
CONCLUSIONThis method is simple, feasible and suitable for industry production.
