Study on chemical constiuents from Ligularia intermedia of shanxi.
- Author:
Hui-qing XUE
1
;
Xue-mei MA
;
Xiao-ning WEI
;
Sui-xian WU
;
Han-qing WANG
Author Information
- Publication Type:Journal Article
- MeSH: Asteraceae; chemistry; Molecular Conformation; Molecular Structure; Plants, Medicinal; chemistry; Sesquiterpenes; chemistry; isolation & purification; Stereoisomerism
- From: China Journal of Chinese Materia Medica 2007;32(11):1044-1047
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the chemical constituents of Ligularia intermedia of Shanxi.
METHODThe compounds were isolated by column chromatography on silica gel and preparative TLC. The structures were identified by IR, MS, 1D/2DNMR spectral data and X-ray single crystal diffraction and other methods1.
RESULTNine compound were isolated and identified as 8beta-hydroxyeremophil-7(11)-ene-12, 8alpha(4beta, 6alpha)-diolide (1), 8beta-methoxyeremophil-7(11)-ene-12, 8alpha(4beta, 6alpha)-diolide (2), petasin (3), isopetasin (4), liguhodgsonal (5), ligudentatol (6), ligujapone (7), lupeol (8) and lupeol palmitate (9).
CONCLUSIONCompounds 2, 3, 4, 6, 7 and 9 were isolated from the plant for the first time.
