Effects of stigma maydis polysaccharide on gastrointestinal movement.
- Author:
Juan DU
1
;
Qi-tai XU
;
Xing-hua GAO
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Cholecystokinin; blood; Drugs, Chinese Herbal; isolation & purification; pharmacology; Female; Gastric Emptying; drug effects; Gastrointestinal Agents; isolation & purification; pharmacology; Gastrointestinal Motility; drug effects; Intestine, Small; physiology; Male; Mice; Plants, Medicinal; chemistry; Polysaccharides; isolation & purification; pharmacology; Random Allocation; Rats; Rats, Wistar; Zea mays; chemistry
- From: China Journal of Chinese Materia Medica 2007;32(12):1203-1206
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the effect of stigma maydis polysaccharide (SMPS) on gastrointestinal movement.
METHODTaking charcoal as the indicator and taking ratio of charcoal movement, beginning time of black excretion and stool amount as the index to observe the effect of SMPS on intestinal movement in mice. Taking emthylorange as the indicator and taking the ratio of residual rate of methylorange as the index to observe the effect of SMPS on gastric emptying in mice. Taking methylene blue as the indicator and taking the time of gastric emptying and movement speed of intestinal content as the index to observe the effect of SMPS on gastrointestinal movement in rats. Observing the changes of cholecystokinin (CCK) level in plasm in rats.
RESULTCompared with control, the ratio of charcoal movement increased in mice (P <0.01). The beginning time of black excretion shortened and the stool amount increased in mice (P <0.01). The ratio of residual rate of methylorange increased in mice (P <0. 01). The time of gastric emptying prolonged in rats (P <0.01). The movement speed of intestinal content in rats accelerated (P <0.01). CCK level in plasm increased in rats (P < 0.05).
CONCLUSIONEffects of stigma maydis polysaccharide on gastrointestinal movement are probably related to the increasing of CCK level in plasm.
