Study on chemical constituents in rhigome of Ervatamia hainanensis.
- Author:
Shuang LIANG
1
;
Hai-sheng CHEN
;
Yong-sheng JIN
;
Li JIN
;
Jia LU
;
Jing-ling DU
Author Information
- Publication Type:Journal Article
- MeSH: Apocynaceae; chemistry; Chromatography, Gel; Ibogaine; analogs & derivatives; chemistry; isolation & purification; Oleanolic Acid; analogs & derivatives; chemistry; isolation & purification; Plants, Medicinal; chemistry; Rhizome; chemistry
- From: China Journal of Chinese Materia Medica 2007;32(13):1296-1299
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the chemical constituents of the rhizome of Ervatamia hainanensis.
METHODThe solvent extraction and silica column chromatography were used to separate the chemical constituents, and their structures were identified by physico chemical properties and spectra analysis.
RESULTTwelve compounds were isolated and their structures were identified as voacangine (1), ibogaine (2), ibogamine (3), coronaridine (4), 19-heyneanine (5), 19-epi-heyneanine (6), 3-hydroxyl coronaridine (7), coronaridine hydroxyindolenine (8), 3-(2-oxopropyl) coronaridine (9), vobasine (10), alpha-amyrin (11), alpha-amyrin acetate (12).
CONCLUSIONCompounds 1, 2, 6, 11 and 12 were first found from this plant.