Clinical significance of glycosylated serum protein in patients with diabetic nephropathy.
- Author:
Pei-lin LI
1
;
Rui YANG
;
Yong ZHOU
;
Hong CHEN
;
De-hong CAI
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Aged, 80 and over; Blood Glucose; analysis; Blood Proteins; analysis; Case-Control Studies; Diabetes Mellitus, Type 2; blood; Diabetic Nephropathies; blood; Female; Glycated Hemoglobin A; analysis; Glycoproteins; analysis; Humans; Male; Middle Aged; Serum; metabolism
- From: Journal of Southern Medical University 2011;31(6):1093-1094
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the relations between fasting blood glucose (FBG), glycosylated hemoglobin A1c (HbA1c) and glycosylated serum protein (GSP).
METHODSFBG, HbA1c and GSP were measured in 303 patients with diabetic nephropathy and in 167 non-diabetic patients with comparable baseline data, and the correlations between FBG, HbA1c and GSP were analyzed.
RESULTSGSP levels were significantly higher in patients with diabetic nephropathy than in the non-diabetic patients (P<0.01). In patients with diabetic nephropathy, GSP levels were found to positively correlate to FBG (r=0.606) and HbA1c (r=0.733).
CONCLUSIONPatients with diabetic nephropathy show strong correlations between FBG, HbA1c and GSP. GSP detection is convenient, stable, and practical in evaluating the average FBG over a short term, which reduces the interference by FBG fluctuations in conventional blood glucose monitoring.
