A Case of Keratitis Caused by Combined Infection of Multidrug-Resistant Acinetobacter Baumannii and Candida Parapsilosis.
10.3341/jkos.2012.53.8.1167
- Author:
Jae Kwang CHOI
1
;
In Hyuk KIM
;
Jeong Won SEO
Author Information
1. Department of Ophthalmology, Sahmyook Medical Center, Seoul, Korea. virgo901@hanmail.net
- Publication Type:Case Report
- Keywords:
Acinetobacter baumannii;
Candida parapsilosis;
Combined infection;
Keratitis;
Multidrug-resistant
- MeSH:
Acinetobacter;
Acinetobacter baumannii;
Akinetic Mutism;
Amphotericin B;
Anti-Bacterial Agents;
Candida;
Corneal Opacity;
Corneal Ulcer;
Eye;
Fluorometholone;
Humans;
Keratitis;
Male;
Middle Aged;
Neurosurgery;
Ofloxacin
- From:Journal of the Korean Ophthalmological Society
2012;53(8):1167-1171
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To report a case of keratitis caused by Acinetobacter baumannii and Candida parapsilosis in a patient using 0.5% levofloxacin and 0.1% fluorometholone for an extended period of time. CASE SUMMARY: A 55-year-old male patient in the neurosurgery department with conjunctival injection and discharge in his left eye was consulted for ophthalmic evaluation and treatment. He was hospitalized in the state of akinetic mutism and given 0.5% levofloxacin and 0.1% fluorometholone for 2 years. On slit-lamp examination, a 3.5 x 4.5-mm dense stromal infiltrate with an overlying epithelial defect was observed. Corneal scraping culture revealed multidrug-resistant A. baumannii and C. parapsilosis. According to the susceptibility result, the patient was treated with topical 10% piperacillin/tazobactam and 0.125% amphotericin B hourly. The corneal ulcer healed gradually with corneal opacity remaining after 8 weeks of treatment. CONCLUSIONS: The authors of the present study report a case of treated multidrug-resistant A. baumannii and C. parapsilosis keratitis in a patient using topical antibiotics and steroid for an extended period of time.
