Risk factors of contrast-induced nephropathy after percutaneous coronary intervention in patients with coronary heart disease and the countermeasures.
- Author:
Hua ZHENG
1
;
Yan TU
;
Li-qin MA
Author Information
- Publication Type:Journal Article
- MeSH: Aged; China; epidemiology; Contrast Media; adverse effects; Coronary Disease; therapy; Female; Humans; Kidney Diseases; chemically induced; epidemiology; prevention & control; Male; Middle Aged; Percutaneous Coronary Intervention; adverse effects; Retrospective Studies; Risk Factors
- From: Journal of Southern Medical University 2011;31(7):1273-1276
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo identify the risk factors of contrast-induced nephropathy (CIN) after coronary interventional therapy (PCI) in patients with coronary heart disease and analyze the clinical outcomes and the preventive measures of CIN.
METHODSNinety-one patients who developed CIN after PCI were retrospectively analyzed to identify the risk factors and explore the preventive measures.
RESULTSCIN was strongly associated with pre-procedural chronic renal failure, diabetes mellitus and administration of large-dose contrast. The incidence of cardiac mortality in hospital or in the follow-up at one year after PCI, and the incidence of myocardial infarction or major adverse cardiac events in the follow-up at one year were obviously higher in patients with CIN than those without CIN.
CONCLUSIONChronic renal failure, diabetes mellitus and large-dose contrast administration are 3 independent risk factors of CIN, which affects the prognosis of the patients. Reinforcement of a comprehensive perioperative management of PCI, especially a rigorous preoperative preparation, can be an important strategy for prevention of CIN.
