Incidence of oral hairy leukoplakia in human immunodeficiency virus-seropositive adult patients in Yunnan, China.
- Author:
Wei-wei ZHAI
1
;
Lei CHEN
;
Jin-song BAI
;
Qin ZHAO
;
Xiang-hong YANG
;
Kai-wen DUAN
Author Information
- Publication Type:Journal Article
- MeSH: Adult; CD4 Lymphocyte Count; Candidiasis, Oral; China; Female; HIV Infections; Humans; Incidence; Leukoplakia, Hairy; Male
- From: West China Journal of Stomatology 2011;29(2):149-152
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the incidence rates, clinical characteristics of oral hairy leukoplakia (OHL) and its relation to the immune status in a sample of human immunodeficiency virus (HIV)-infected adults in Yunan, China.
METHODS1 060 adult patients with HIV from January 2008 to June 2010 were evaluated. The age, gender, education grade, diagnosis time of HIV-infected, route of transmission, xerostomia, oral candidiasis, high active antiretroviral therapy and CD4 lymphocytes counts. The occurrence of OHL was recorded by oral examination. The relationship of CD4 lymphocytes counts and the incidence of OHL were analyzed by statistical methods.
RESULTSThere were 94 OHL patients in 1 060 HIV patients (8.9%). The average age of the OHL patients was (39.33 +/- 10.45) years old. 90% OHL was found on the two lateral aspect of the tongue. The CD4 lymphocytes of 70.2% OHL patients were less than 200 mm-3.
CONCLUSIONOHL is a frequent finding in patients with indicates severe immunosuppression and associated with the reduction of CD4 lymphocytes.
