Serum insulin levels in newly diagnosed type II diabetics during emergency care
- Author:
Anh Dat Nguyen
- Publication Type:Journal Article
- Keywords:
diabete
- MeSH:
Insulin;
Diabetes Mellitus, Type 2;
Serum;
Emergency Medical Services
- From:Journal of Practical Medicine
1998;344(1):26-28
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Purpose of this study was to measure the serum insulin level in 23 newly diagnosed type II diabetics during acute stress. Diagnosis of diabetes was based on the criteria recommended by WHO in 1986 and the serum fructosamine level more than 290 mol/L. Method: Patients were measured the insulin level on venous blood samples by ELISA method with Roche’s reagent and ES-33 apparatus. Turner’s equation was applied to evaluate the relationship between serum insulin and glucose level and to assess the insulin resistance (reference range is 0-30 and a value >50 was considered the insulin resistance). Result: The mean serum insulin level of the studied patients was 35.55.5 U/mL, with the values ranged from 5.97 to 131.34 U/mL. Out of 23 patients, only 3 (13%) had serum insulin levels in a normal range (i.e. in a reference interval of 3.68-7.67U/mL). 20 patients (83%) had higher insulin levels than reference. Assessing the insulin resistance by Turner’s equation showed that only 2 of 23 patients (8.6%) had a normal ratio (i.e. less than 50), almost patients in this study (21/23; 91.4%) were more than 50 in ratio, suggested an evident insulin resistance. Especially, 10/23 patients (43.8%) reached a value of more than 100, indicated the severe hyperinsulinemia. Conclusion: 83% of our patients with newly diagnosed type II diabetes showed the hyperinsulinemia during acute stress. Almost these patients (more than 90%) presented the strong evidence of insulin resistance.
