Current study and application of human colorectal cancer cell lines.
- Author:
Keling CHEN
1
;
Zhaoying LYU
;
Zongguang ZHOU
;
Yuan LI
Author Information
1. Institute of Digestive Surgery, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China. liyuanletters@163.com.
- Publication Type:Journal Article
- MeSH:
Cell Line;
Colorectal Neoplasms;
Humans
- From:
Chinese Journal of Gastrointestinal Surgery
2015;18(1):93-97
- CountryChina
- Language:Chinese
-
Abstract:
Colorectal cancer(CRC) cell lines are ideal in vitro models for colorectal cancer study. Although the number of colorectal cell lines increases hence provides diversified choices for research, several problems occur including the uneven quality control, insufficient attention to the origin and biological characteristics of CRC cell lines, resulting in inappropriate selection of CRC cell lines for study. In this paper, we classify the current CRC cell lines for study, review the biological characteristics, current problems of experiment choices, and discuss the exact choice of cell lines for CRC study.
