Clinical study on treatment of non-alcoholic fatty liver of damp-heat syndrome type by danning tablet.
- Author:
Guang JI
1
;
Jian-gao FAN
;
Jian-jie CHEN
Author Information
- Publication Type:Clinical Trial
- MeSH: Adult; Diagnosis, Differential; Double-Blind Method; Drugs, Chinese Herbal; therapeutic use; Fatty Liver; classification; drug therapy; Female; Humans; Male; Medicine, Chinese Traditional; Middle Aged; Phytotherapy; Tablets; Treatment Outcome
- From: Chinese Journal of Integrated Traditional and Western Medicine 2005;25(6):485-488
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the therapeutic effect of Danning Tablet (DNT) on patients with non-alcoholic fatty liver (NAFL) of damp-heat Syndrome type.
METHODSMulti-center randomized double-blinded positive medicine parallel controlled method was adopted. One hundred and two patients were treated with DNT and 33 patients treated with Ursodeoxycholic acid (UDCA) as control. Indexes including body mass index (MBI), principal symptom, liver function, blood lipids, iconographic parameters and comprehensive efficacy were measured before and after treatment in the two groups respectively.
RESULTSDNT and UDCA had the effect in improving BMI, distress in hepatic region, fatigue, anorexia, liver function, blood lipids and iconographic parameters, etc. DNT showed effects in improving BMI and distress in hepatic region better than those of UDCA. Histological examination also showed that DNT had good therapeutic effect.
CONCLUSIONDNT is an effective medicine for NAFL patients of damp-heat Syndrome type, and its efficacy is better than that of UDCA.