Clinical observation on effect of shenqi fanghou recipe in preventing and treating radiation injury in patients with head and neck tumor.
- Author:
Yue-ran HU
1
;
Chao-quan WU
;
Ya-jie LIU
;
Yaobang WANG
;
Xianming LI
;
Heli ZHONG
;
Yujiao YU
Author Information
- Publication Type:Clinical Trial
- MeSH: Adult; Aged; Combined Modality Therapy; Drugs, Chinese Herbal; therapeutic use; Female; Head and Neck Neoplasms; drug therapy; radiotherapy; Humans; Male; Middle Aged; Phytotherapy; Radiation Injuries; drug therapy; prevention & control
- From: Chinese Journal of Integrated Traditional and Western Medicine 2005;25(7):623-625
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the therapeutic effect of shenqi fanghou recipe (SFR) in preventing and treating radiation injury in patients with head and neck tumor.
METHODSOne hundred and forty patients with head and neck tumor, including nasopharyngeal carcinoma, carcinoma of tonsil or tongue, were randomly divided into 2 groups, 70 patients in the observed group were given modified SFR as adjuvant to radiotherapy, while 70 patients in the control group were treated with radiotherapy alone. The radiation reactions during radiotherapy and the condition of late stage radiation injury radiotherapy in patients in the 2 groups were observed.
RESULTSThe degree of oropharyngeal mucosa reaction, dryness in mouth and radiation dermatitis in cervical region in the observed group was milder than those in the control group, and the radiation injury induced late stage sequelae, such as the degree of mouth-opening was better and the cervical muscular sclerosis was better in the observed group than in the control group, showing significant difference (P < 0.01).
CONCLUSIONSFR has definite effect in preventing and treating radiation reaction and late stage radiation injury in patients with head and neck tumor.
