Research progress in sperm mediated gene transfer technology.
- Author:
Xiaoxiong HAO
1
;
Zheng ZHU
;
Mianfu CAO
;
Chengren LI
;
Yunlai LIN
Author Information
1. Company Four, Third Military Medical University, Chongqing 400038, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Animals, Genetically Modified;
Gene Transfer Techniques;
Genetic Engineering;
methods;
Male;
Sperm Transport;
physiology;
Spermatozoa;
metabolism;
physiology
- From:
Journal of Biomedical Engineering
2013;30(2):443-446
- CountryChina
- Language:Chinese
-
Abstract:
With the rapid development of biotechnology, we can change the trait of organism using transgenetic technology. In recent years, there are growing interests in the establishment of sperm mediated gene transfer (SMGT) technology as an effective and convenient method to produce transgenic animals. SMGT technology is a transgenetic method, which is easy in operation and does little harm to the cell compared with the other transgenetic methods. In this review, we expound the background, development, mechanism, operation and application of SMGT.
