Advances in treatment of myocardial infarction by mesenchymal stem cell transplantation .
- Author:
Huizhu CHEN
;
Yingkun GUO
;
Gang NING
- Publication Type:Journal Article
- MeSH:
Cell Differentiation;
Hematopoietic Stem Cells;
Humans;
Mesenchymal Stem Cell Transplantation;
Mesenchymal Stromal Cells;
Myocardial Infarction;
therapy
- From:
Journal of Biomedical Engineering
2014;31(4):939-944
- CountryChina
- Language:Chinese
-
Abstract:
Mesenchymal stem cells(MSCs)is a kind of non hematopoietic stem cell from the mesoderm, which can self renew, proliferate and perform multilineage differentiation. Due to the characteristics of acquiring easily and low immunogenicity, it has become the main cell for myocardial infarction. In this article, the biology and the immunology of the MSCs is reviewed, the safety and the validity of the therapy on myocardial infarction with MSCs and the HGF/MSCs is introduced. And furthermore, it also explains the possible mechanism and the problems of how to improve the cardial function.
