Study of the RNA secondary structure prediction.
- Author:
Ying SUN
;
Hongwei LU
;
Jianbin GUI
;
Xuekun SONG
- Publication Type:Journal Article
- MeSH:
Algorithms;
Nucleic Acid Conformation;
RNA;
chemistry
- From:
Journal of Biomedical Engineering
2014;31(5):1065-1069
- CountryChina
- Language:Chinese
-
Abstract:
This paper proposes algorithm in predicting the RNA secondary structure that combines several sequence comparisons, searches the eigenvalue for subsequence division with dynamic programing, utilizing the minimum free energy method. Moreover, the paper assesses the results derived from this new algorithm based on base-pairs distance, climbing distance and morphology distance. The paper also compares the assessment result and the prediction results of different prediction tools, and analyzes the advantages of the new method and its improvement direction.
