Molecular regulation of skeletal satellite cell's self-renewal.
- Author:
Hui XIONG
;
Yabin PU
;
Yuehui MA
;
Qingyun HU
;
Weijun GUAN
;
Xiangchen LI
- Publication Type:Journal Article
- MeSH:
Cell Proliferation;
Humans;
Muscle, Skeletal;
Regeneration;
Satellite Cells, Skeletal Muscle;
cytology;
Soft Tissue Injuries
- From:
Journal of Biomedical Engineering
2014;31(5):1168-1171
- CountryChina
- Language:Chinese
-
Abstract:
Skeletal muscle possesses a remarkable ability for its regeneration and injured tissue repair. This ability depends on the activity and contributions of muscle satellite cells. Proliferating satellite cells, termed myogenic precursor cells or myoblasts, are activated and driven out of their quiescent state upon muscle injury. In this summary, we present a review to summarize the molecular regulation in skeletal satellite cells to light on the satellite cells' self-renewal mechanism.