Surveillance on pathogens of meningococcal meningitis in Beijing, 2005.
- Author:
Tie-gang ZHANG
1
;
Xiong HE
;
Li-juan CHEN
;
Jing-guo HE
;
Jie YANG
Author Information
- Publication Type:Journal Article
- MeSH: China; DNA, Bacterial; analysis; Electrophoresis, Gel, Pulsed-Field; Humans; Meningitis, Meningococcal; microbiology; Neisseria meningitidis, Serogroup A; genetics; isolation & purification; Polymerase Chain Reaction; Sequence Analysis, DNA
- From: Chinese Journal of Epidemiology 2006;27(5):396-398
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the pathogens of meningococcal meningitis (MM) in Beijing, 2005.
METHODSBlood and cerebrospinal fluid specimens from MM patients were detected by polymerase chain reaction. Bacterial strains were analyzed by pulsed-field gel electrophoresis and multilocus sequence typing.
RESULTS7 of the blood and 5 of cerebrospinal fluid specimens showed positive results. 105 of the Neisseria meningitides strains were isolated from the specimens of patients, close contacts and healthy carriers. Serogroup A and C Neisseria meningitides strains shared the same patterns of pulsed-fieldgel electrophoresis, respectively. The sequence type of serogroup A Neisseria meningitides belonged to ST7 while the sequence type of serogroup C Neisseria meningitides belonged to ST4821.
CONCLUSIONPatients suffered from meningococcal meningitis were caused by serogroup A (ST7) and C (ST4821) Neisseria meningitides in Beijing, 2005.
