Progress on the research of microRNA and its functions in lymphoid malignancies--review.
- Author:
Wei XU
1
;
Jian-Yong LI
;
Feng-Xiang LU
Author Information
1. Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Humans;
Leukemia, Lymphoid;
genetics;
Lymphoma;
genetics;
Lymphoproliferative Disorders;
genetics;
MicroRNAs;
biosynthesis;
genetics;
RNA, Small Interfering;
genetics
- From:
Journal of Experimental Hematology
2006;14(4):840-844
- CountryChina
- Language:Chinese
-
Abstract:
Plant and animal genomes contain an abundance of small genes that produce RNAs of about 22 nucleotides in length, which was dubbed as microRNA (miRNA). These newly found endogenous RNAs may participate in a wide range of genetic regulatory pathways and play an important role in the organism development. This paper reviewed the recent studies and progress on the characteristics, functions and mechanisms of the microRNAs, as well as the advances of research on lymphoid malignancies.
