Frequncy and etiology of lymphadenopathy in Iranian HIV/AIDS patients.

Azar Hadadi; Sirous Jafari; Zahra Hoseini Jebeli; Reza Hamidian

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Frequncy and etiology of lymphadenopathy in Iranian HIV/AIDS patients.

Author: Azar HADADI ^{1
,

2} ; Sirous JAFARI ³ ; Zahra Hoseini JEBELI ⁴ ; Reza HAMIDIAN ⁵
Author Information

1. Iranian Research Center for HIV/AIDS Institute of High Risk Behavior Reduction, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran
2. Internal Medicine Department & Research Development Center, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.
3. Infectious Diseases Department and Iranian Research Center for HIV/AIDS, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
4. Candidate for Radiology, Tehran University of Medical Sciences, Tehran, Iran.
5. Research Development Center, Sina hospital, Tehran University of Medical Sciences, Tehran, Iran.
Publication Type:Journal Article
Keywords: AIDS; Etiology; HIV; Lymphadenopathy
From:Asian Pacific Journal of Tropical Biomedicine 2014;4(Suppl 1):S171-6
CountryChina
Language:English
Abstract:
OBJECTIVETo estimate and outline the frequency and etiology of lymphadenopathy in HIV/AIDS patients.
METHODSThis study was conducted on 178 consecutive HIV/AIDS patient files for etiologies (categorized into three sub-groups: definite, probable and possible) and associated factors of local and generalized lymphadenopathy.
RESULTSSeventy-two (40.45%) patients including 63 male patients (87.5%) developed lymphadenopathy. HIV in lymphadenopathy(+) patients was most commonly transmitted intravenously (n=49). Generalized and localized lymphadenopathy respectively occurred in 27 (37.50%) and 45 (62.50%) patients, mainly in the cervical region (28.9% for local and 63% for generalized lymphadenopathy). The most common causes of lymphadenopathy were tuberculosis (n=24, 33.3%) and lymphoma (n=12, 16.6%). The frequency of lymphadenopathy was non-significantly higher in patients with AIDS (CD4 count <200 cell/µL) vs. HIV(+) patients (CD4 count >200 cell/µL).
CONCLUSIONSLymphadenopathy in HIV/AIDS patients may reflect a serious condition, most likely tuberculosis and lymphoma. Since patients might underestimate lymphadenopathy, physicians would rather list these entities for diagnosis.