Guillain-Barre Syndrome With anti-GM1 and GD1b Antibodies Following Acute Hepatitis A.
- Author:
Sang Soon PARK
1
;
Young NOH
;
Se Ho OH
;
Yoon Ho HONG
;
Seong Ho PARK
Author Information
1. Department of Neurology, Seoul National University College of Medicine, Seoul, Korea. nrpsh@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Acute Hepatitis A;
Guillain-Barre syndrome;
anti-ganglioside antibody
- MeSH:
Adult;
Antibodies;
Gangliosides;
Guillain-Barre Syndrome;
Hepatitis;
Hepatitis A;
Humans;
Immunoglobulin G;
Neural Conduction;
Polyneuropathies;
Quadriplegia
- From:Journal of the Korean Neurological Association
2008;26(4):379-382
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Guillain-Barre syndrome (GBS) rarely develops following acute viral hepatitis, and there has been no report on the association with anti-ganglioside antibodies. Herein, we report a 36-year-old man who presented with rapidly progressive areflexic quadriparesis following acute viral hepatitis A. The results of nerve conduction study were consistent with demyelinating motor polyneuropathy, and IgG anti-GM1 and anti-GD1b antibodies were positive. Immune responses towards gangliosides may also be important mediators in acute hepatitis A-associated GBS.
