Iridoid glycosides from buds of Jasminum officinale L. var. grandiflorum.
- Author:
Gui-qin ZHAO
1
;
Zhi-feng YIN
;
Yu-cui LIU
;
Hong-bo LI
Author Information
1. Hebei Key Laboratory of Research and Development for Traditional Chinese Medicine, Institute of Chinese Materia Medica, Chengde Medical College, Chengde 067000, China. zhaoguiqin1971@sina.com.cn
- Publication Type:Journal Article
- MeSH:
Antiviral Agents;
chemistry;
isolation & purification;
pharmacology;
Flowers;
chemistry;
Glucosides;
chemistry;
isolation & purification;
pharmacology;
Hep G2 Cells;
Hepatitis B Surface Antigens;
metabolism;
Hepatitis B virus;
immunology;
Humans;
Inhibitory Concentration 50;
Iridoid Glucosides;
chemistry;
isolation & purification;
Iridoid Glycosides;
chemistry;
isolation & purification;
pharmacology;
Iridoids;
chemistry;
isolation & purification;
Jasminum;
chemistry;
Molecular Structure;
Plants, Medicinal;
chemistry
- From:
Acta Pharmaceutica Sinica
2011;46(10):1221-1224
- CountryChina
- Language:Chinese
-
Abstract:
The study on the buds of Jasminum officinale L. var. grandiflorum was carried out to look for anti-HBV constituents. The isolation and purification were performed by HPLC and chromatography on silica gel, polyamide and Sephadex LH-20 column. The structures were elucidated on the basis of physicochemical properties and spectral analysis. Six iridoid glycosides were identified as jasgranoside B (1), 6-O-methy-catalpol (2), deacetyl asperulosidic acid (3), aucubin (4), 8-dehydroxy shanzhiside (5), and loganin (6). Jasgranoside B (1) is a new compound. Compounds 2-6 were isolated from Jasminum officinale L. var. grandiflorum for the first time.
