Acute toxicity assay of pancreatine product in white mice
- Author:
Tiet Thi Nguyen
- Publication Type:Journal Article
- Keywords:
pancreatine
- MeSH:
Acute Toxicity Tests;
Poisoning
- From:Pharmaceutical Journal
2002;318(10):22-23
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The maximal doses of Pancreatine, in concentrations of 1.5%o and 3%o that can be given in mice, equivalent 0.450g/1ml distilled water/mouse (preparation 1.5%o and 0.90g/1ml distilled water/mouse (preparation 3%o, ie 200 times the dose for pigs, were administered in mice orally. After the trial of acute toxicity, our finding are as follows: After 72 hours signs of poisoning or deaths were not observed. LD50 could not be determined because of the potential low toxicity of the product
