Comparison of dissolution properties between Ginseng micropowder and common powder.
- Author:
Lu CAI
1
;
Shaoyu LIANG
;
Kaijin DAI
;
Feijun XIANG
;
Qizhi LUO
Author Information
- Publication Type:Journal Article
- MeSH: Chromatography, High Pressure Liquid; Ginsenosides; analysis; chemistry; Panax; chemistry; Particle Size; Plant Roots; chemistry; Plants, Medicinal; chemistry; Powders; chemistry; Solubility
- From: Journal of Southern Medical University 2013;33(10):1547-1550
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo compare the dissolution properties of Ginseng micropowder and common powder in vitro and investigate the effect of micronization on dissolution of Ginseng.
METHODSFive ginsenosides including Rg1, Re, Rf, Rb1, and Rb2 were determined by high performance liquid chromatography, and the dissolution curves of Ginseng micropowder and common powder were drawn.
RESULTSThe dissolution rates of ginsenosides from micropowder exceeded 90% within 5 min, significantly greater than that from common powder. But when the powders were packed in tea bags, the dissolution rates of ginsenosides were higher from common powder than from micropowder.
CONCLUSIONMicronization treatments can promote dissolution of ginsenosides from Ginseng.
