Two Cases of Metronidazole-Induced Neurotoxicity Lacking of Clinico-Radiological Correlation.
- Author:
Kyum Yil KWON
1
;
Dae Kyoon LEE
;
Ka Hyun LEE
;
Kyung Hee CHO
;
Eugene LEE
;
Sun Ju CHUNG
Author Information
1. Department of Neurology, University of Ulsan College of Medicine, Seoul, Korea. sjchung@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Metronidazole;
Neurotoxicity;
Brain MRI
- MeSH:
Amebiasis;
Bacterial Infections;
Brain;
Giardiasis;
Humans;
Magnetic Resonance Imaging;
Metronidazole
- From:Journal of the Korean Neurological Association
2006;24(6):581-584
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Metronidazole is an antimicrobial agent widely used for the treatment of trichomoniasis, giardiasis, amebiasis, and anaerobic bacterial infections. It has been reported that metronidazole-induced neurotoxicity is associated with responsible lesions on brain MRI. We report 2 patients with metronidazole-induced neurotoxicity, who had no responsible lesions on brain MRI for their neurological deficits. The pathogenic mechanisms are discussed.
