Association of serum decoy receptor 3 protein level with the clinicopathologic features of bladder transitional cell carcinoma.
- Author:
Dong WANG
1
;
Jian WANG
;
Guojun CHEN
Author Information
- Publication Type:Journal Article
- MeSH: Carcinoma, Transitional Cell; blood; Enzyme-Linked Immunosorbent Assay; Humans; Receptors, Tumor Necrosis Factor, Member 6b; blood; Urinary Bladder Neoplasms; blood
- From: Journal of Southern Medical University 2013;33(12):1831-1832
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the association of serum levels of decoy receptor 3(DcR3) protein and the clinicopathologic features of bladder transitional cell carcinoma.
METHODSEnzyme-linked immunosorbent assay was used to examine the serum levels of DcR3 in patients with bladder transitional cell carcinoma for analysis of its association with the patients' age, gender, clinical stages and pathological classification.
RESULTSThe patients with bladder transitional cell carcinoma showed a significantly elevated serum level of DcR3 (183.43 ∓78.45 pg/m1) compared with the normal level (116.65∓97.43 pg/m1, P<0.05). The serum level of DcR3 in the patients showed close correlations with the TNM stage and pathological classification of the tumor (P<0.05) but not with the patients' age or gender (P>0.05).
CONCLUSIONSIn patients with bladder transitional cell carcinoma, a high serum level of DcR3 suggests a higher malignancy of the tumor.
