A Case of Morvan Syndrome.
- Author:
Seon Gyeong KIM
1
;
Seok Beom KWON
;
Ki Han KWON
;
San JUNG
;
Sung Hee HWANG
Author Information
1. Department of Neurology, Hallym University College of Medicine, Seoul, Korea. neukwon@hallym.ac.kr
- Publication Type:Case Report
- Keywords:
Lsaacs' syndrome;
Neuromyotonia;
Morvan's syndrome
- MeSH:
Anorexia;
Antibodies;
Dihydroergotamine;
Hallucinations;
Humans;
Hyperhidrosis;
Isaacs Syndrome;
Lower Extremity;
Myokymia;
Peripheral Nerves;
Rare Diseases;
Sleep Initiation and Maintenance Disorders;
Young Adult
- From:Journal of the Korean Neurological Association
2006;24(6):585-588
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Neuromyotonia, or Isaacs' syndrome, consists of continuous muscle fiber activity caused by hyperexcitability of the peripheral nerves. Rarely, these patients also develop CNS symptoms characterized by confusion, insomnia, hallucinations, and agitation. A rare disease consisting of neuromyotonia, autonomic symptoms, and CNS dysfunction is called Morvan's syndrome. We report a 24-year-old man who presented with insomnia, malaise, anorexia, hyperhidrosis, palpitation and myokymia in both the lower extremities. The pathomechanism of Morvan's syndrome is related to the voltage-gated K+ channel (VGKC) antibodies.
