Association of NMDAR, NR2A, and NR2B with cognitive impairment in diabetic patients.
- Author:
Xiaopeng WANG
1
;
Yongjie HUANG
;
Fang WANG
;
Yingying ZOU
Author Information
1. Department of Pathology and Pathophysiology, Faculty of Basic Medical Science, Kunming Medical University, Kunming 650500, China. E-mail: 261334618@qq.com.
- Publication Type:Journal Article
- MeSH:
Central Nervous System;
Cognition Disorders;
complications;
genetics;
Diabetes Mellitus;
physiopathology;
Humans;
Memory;
Receptors, N-Methyl-D-Aspartate;
metabolism
- From:
Journal of Southern Medical University
2013;33(12):1848-1851
- CountryChina
- Language:Chinese
-
Abstract:
Cognitive impairment in diabetes (CID) is a severe chronic complication of diabetes mellitus, and its pathogenesis has not yet been fully understood. Increasing evidence has shown that the distribution and expression of N-methyl-D-aspartame receptor (NMDAR) and subunits NR2A and NR2B, which all participated in the development of the central nervous system and formation of learning and memory, are correlated with the occurrence and development of CID.
