Fucoidan: advances in the study of its anti-inflammatory and anti-oxidative effects.
- Author:
Yan-qiu CUI
1
;
Ding-zhen LUO
;
Xiao-min WANG
Author Information
1. Key Laboratory of Neurodegenerative Disorders of the Ministry of Education, Department of Physiology, Capital Medical University, Beijing 100069, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Anti-Inflammatory Agents;
isolation & purification;
metabolism;
pharmacology;
Antioxidants;
isolation & purification;
pharmacology;
Polysaccharides;
isolation & purification;
metabolism;
pharmacology;
Reactive Oxygen Species;
metabolism;
Receptors, Scavenger;
metabolism;
Seaweed;
chemistry;
Selectins;
metabolism
- From:
Acta Pharmaceutica Sinica
2008;43(12):1186-1189
- CountryChina
- Language:Chinese
-
Abstract:
Fucoidan is a natural polysaccharide extracted from brown seaweeds, with a wide variety of biological features, especially the anti-inflammatory and anti-oxidative effects. Studies indicated that the anti-inflammatory effect of fucoidan related to its capacity to interact with the selectin or scavenger receptor on the cell membrane. Fucoidan can also inhibit the synthesis and release of reactive oxygen species (ROS), as well as promote its clearance, showing the anti-oxidative activity.
