Seperation and structure elucidation of alkaloids from Chinese drug buzhaye, Folium Microcos.
- Author:
Ji-Peng LUO
1
;
Li-Ping ZHANG
;
Shi-Ling YANG
;
M F ROBERTS
;
J D PHILLIPSON
Author Information
1. Guangdong College of Pharmacy, Guangzhou 510006, China. jason.lam@163.com
- Publication Type:Journal Article
- MeSH:
Alkaloids;
chemistry;
isolation & purification;
Molecular Structure;
Piperidines;
chemistry;
isolation & purification;
Plant Leaves;
chemistry;
Plants, Medicinal;
chemistry;
Tiliaceae;
chemistry
- From:
Acta Pharmaceutica Sinica
2009;44(2):150-153
- CountryChina
- Language:Chinese
-
Abstract:
From the chloroform extracts of the dried Folium Microcos, four compounds were isolated by using repeated column chromatography on silica gel and recrystallization and their structures were elucidated by physicochemical properties and UV, MS and NMR, separately. They are N-methyl-6alpha-(deca-1', 3', 5'-trienyl)-3beta-methoxy-2beta-methylpiperidine, 6-(deca-1', 3', 5'-trienyl)-3-methoxy-2-methylpiperidine, N-methyl-6-(deca-1', 3', 5'-trienyl)-2, 3-dimethylpiperidine and N-methyl-6-(deca-1', 3', 5'-trienyl)-2-methylpiperidine, named as micropiperidine A, micropiperidine B, micropiperidine C and micropiperidine D, respectively. The latter three are new compounds.
