Progress of research on microRNA and Alzheimer's disease.
10.3760/cma.j.issn.1003-9406.2013.01.015
- VernacularTitle:小RNA与阿尔茨海默病发病机制研究进展
- Author:
Shu-hui DONG
1
;
Tao WANG
;
Shi-fu XIAO
Author Information
1. Shanghai Jiaotong University School of Medicine, Shanghai, People's Republic of China.
- Publication Type:Journal Article
- MeSH:
Alzheimer Disease;
genetics;
metabolism;
Animals;
Humans;
MicroRNAs;
genetics;
metabolism
- From:
Chinese Journal of Medical Genetics
2013;30(1):64-66
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNA are a group of non-coding RNA which, through regulating expression of proteins at post-transcription level, plays an important role in modulating growth and development of nervous system, cell differentiation and functions. Altered expression of microRNA in the brain may influence development and advance of Alzheimer's disease from multiple perspectives. Research on microRNA will facilitate in depth understanding of the pathogenesis of Alzheimer's disease.
