Effects of androgen on lipoprotein and the cardiovascular system.
- Author:
Jing-Wen LI
1
;
Yi-Qun GU
Author Information
1. Peking Union Medical College, Beijing 100730, China.
- Publication Type:Journal Article
- MeSH:
Androgens;
pharmacology;
physiology;
Cardiovascular System;
drug effects;
Female;
Humans;
Lipoproteins;
metabolism;
Male;
Polymorphism, Genetic;
Receptors, Androgen;
genetics;
physiology
- From:
National Journal of Andrology
2007;13(10):928-931
- CountryChina
- Language:Chinese
-
Abstract:
The effects of androgen on lipid and the cardiovascular system are very important. The relationship between androgen and lipoprotein is rather complicated and influenced by many factors. The effects of endogenous androgen on the metabolism of lipoprotein vary with age, environment, nutrition and gender, while the effects of exogenous androgen on lipoprotein vary with different androgen preparations, administration methods and diseases to be treated. Androgen can impact the metabolism of lipoprotein, vascular endothelium, macrophage, vascular smooth muscle, angiotasis, blood coagulation, platelet and so on. The effects of polymorphism of the androgen receptor gene CAG on the cardiovascular system are important and yet somehow controversial and have to be further investigated.
