Indocyanine Green Enhanced Photocoagulation in the Pigmented Rabbit.
- Author:
Young Keun SHIN
1
;
Boo Sup OUM
Author Information
1. Department of Ophthalmology, College of Medicine, Pusan National University, Pusan, Korea.
- Publication Type:Original Article
- Keywords:
Diode laser;
Dye enhanced photocoagulation;
Indocyanine green
- MeSH:
Administration, Intravenous;
Burns;
Indocyanine Green*;
Lasers, Semiconductor;
Light Coagulation*;
Rabbits;
Retinaldehyde
- From:Journal of the Korean Ophthalmological Society
1995;36(10):1706-1712
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Diode laser photocoagulation was performed in the pigmented rabbits, after intravenous administration of the Indocyanine green(4mg/kg). Exposure time and spot size were fixed at 0.2 second and 200um, and laser power varied in the range of 200-250mW to achieve gray-white burn. Ophthalmoscopic examination 1 hour later revealed that whitish photocoagulated lesion appeared somewhat larger in the ICG- administrated group than in the control. Depigmented border of the lesion appeared more distinct in the ICG- administrated group than in the control at 1 week later. There was no distinct difference between both groups at 1 month later. Histopathologically, degree of retinal damage was similar in both groups, but occlusion of choriocapillaris was more severe in the ICG- administrated group than in the control.
