Kappa Chain Monoclonal Primary Cutaneous Plasmacytoma.
- Author:
Ki Hun CHUNG
1
;
Min Jung LEE
;
Dong Kyun KO
;
Joon Soo PARK
;
Hyun CHUNG
Author Information
1. Department of Dermatology, College of Medicine, The Catholic University of Daegu, Daegu, Korea. g9563009@cu.ac.kr
- Publication Type:Case Report
- Keywords:
Kappa chain;
Monoclonality;
Primary cutaneous plasmacytoma
- MeSH:
Aged;
Biopsy;
Dermis;
Humans;
Immunoglobulin kappa-Chains;
Lymphoma, B-Cell;
Plasma Cells;
Plasmacytoma;
Skin
- From:Korean Journal of Dermatology
2010;48(12):1114-1117
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary cutaneous plasmacytoma is a rare type of cutaneous B-cell lymphoma that arises primarily in the skin, and this is derived from clonally expanded plasma cells with various degrees of maturation and atypia. A 72-year-old man had an asymptomatic, solitary reddish to violaceous nodule on the back for about 4 months. The histologic finding of the skin biopsy specimen demonstrated an infiltration of variably matured plasma cells in the dermis, and these cells showed a monotypic expression of immunoglobulin kappa chains on immunohistochemical staining. Staging investigations excluded any extracutaneous manifestations of the disease. Only a few cases of primary cutaneous plasmacytoma have been published in the Korean dermatologic literature. Herein, we report on an interesting case of primary cutaneous plasmacytoma with monoclonality of kappa chains.
