Molecular biological progress of hepatocyte growth factor (HGF).
- Author:
Shui-Liang YU
1
;
Fu-Hua YANG
Author Information
1. College of Life Science, Wuhan University, Wuhan 430072, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Gene Expression Regulation;
Genetic Therapy;
Genetic Variation;
Hepatocyte Growth Factor;
chemistry;
genetics;
Humans;
Promoter Regions, Genetic;
Protein Engineering;
RNA Splicing;
genetics
- From:
Chinese Journal of Biotechnology
2002;18(1):1-4
- CountryChina
- Language:Chinese
-
Abstract:
Hepatocyte growth factor (HGF) is a multifunctional growth factor which is a heterodimeric glycoprotein molecule. There are three truncated HGF variants: NK1, NK2, NK4. The structure of the promoter of HGF is very complicated, and the expression of HGF is regulated by various factors and regulatory elements. Because of the importance of HGF to human body, the genetic engineering expression and gene therapy investigation of HGF are being done.
