Protein microarrays and their medical applications.
- Author:
Rui-Zhe JIA
1
;
Li JIANG
;
Zu-Ming TANG
Author Information
1. Southeast University Clinical Medical College, Nanjing 210009, China. rzjia@263.net
- Publication Type:Journal Article
- MeSH:
Biomedical Research;
Proteins;
analysis
- From:Chinese Journal of Biotechnology
2002;18(2):246-248
- CountryChina
- Language:Chinese
-
Abstract:
The microarrays have revolutionised biomedical experimentation and diagnostics, enabling ordered high throughput analysis. During the past decade, classic solid phase substrates, such as microlitre plates, membrane filters and microscopic slides, were turn into high-density, chip-like structure. The concept of the arrayed library was central to this development which now extends from DNA to protein. The availability of such protein microarrays would facilitate the simultaneous analysis of thousands of interactions within a single experiment. They can be utilized for massively parallel testing of protein function or recognized their target polypeptide in complex biological solution. This article will focus on the current strategies used to generate protein microarray and their applications in biological research, medicine and diagnostics.
