The development of peptide nucleic acid in gene regulation.
- Author:
Xia GONG
1
;
Guo-Wei LE
;
Yong-Hui SHI
Author Information
1. Food College of Southern Yangtze University, Wuxi 214036, China. gongxia11@263.net
- Publication Type:Journal Article
- MeSH:
Gene Expression Regulation;
drug effects;
Peptide Nucleic Acids;
pharmacology;
Protein Biosynthesis;
drug effects;
Transcription, Genetic;
drug effects
- From:
Chinese Journal of Biotechnology
2002;18(3):282-285
- CountryChina
- Language:Chinese
-
Abstract:
Peptide nucleic acid(PNA) is a kind of artificial DNA mimic. PNA hybridizes with DNA or RNA by means of Watson-Crick's base-pairs complementary with high stability, affinity and selectivity. PNA not only regulates. DNA replication, but also adjusts DNA transcription (or reverse transcription) and translation. Many applications have been explored as a new kind of molecular biological tool and a gene-targeting strategy.
