The research of saffold virus in children with lower respiratory tract infection in Changsha.
- Author:
Qiong-hua ZHOU
1
;
Bing ZHANG
;
Zhi-ping XIE
;
Han-chun GAO
;
Ming-wei GUO
;
Fei ZHANG
;
Kun-long YAN
;
Rong-fang ZHANG
;
Jing ZHANG
;
Chang-qing CAO
;
Zhao-jun DUAN
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Cardiovirus; genetics; isolation & purification; Child; Child, Preschool; China; Female; Humans; Infant; Infant, Newborn; Male; Polymerase Chain Reaction; Respiratory Tract Infections; virology
- From: Chinese Journal of Experimental and Clinical Virology 2011;25(1):8-10
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate prevalence of Saffold virus (SAFV) in Changsha area of hospitalized children with respiratory tract infection, and to discuss whether this virus is related to respiratory tract infection of children.
METHODS643 nasopharyngeal aspirates samples were collected from hospitalized children with respiratory tract infection of the first affiliated hospital of Hunan nomal university during Nov. 2007 to Oct. 2008. Real-time fluorescent quanti-tative PCR(FQ-PCR) performed to screen the 5'UTR gene. And then analyze clinical data.
RESULTSSAFV were detected in 67 patients (10.42%) out of the 643 children, it was not detected over 5 years of age. The virus were detected in 8 patients (25.81%) out of the 31 children with persistent pneumonia and chronic pneumonia, there was statistically significant.
CONCLUSIONThere existed SAFV infection in hospitalized children with lower respiratory infection in Changsha area; SAFV maybe related to disease onset with lower respiratory tract infection of children.
