Study of human papillomavirus in biopsy tissue specimens of esophageal carcinomas in Linzhou city
10.3760/cma.j.issn.1003-9279.2011.01.014
- VernacularTitle:林州市地区食管癌活检组织中人乳头瘤病毒的研究
- Author:
Ming-Chen CUI
1
;
Ying LI
;
Xin HE
;
Xiao-Li WANG
;
Li-Dong WANG
;
Hong-Tu LIU
Author Information
1. 漯河医学高等专科学校
- Keywords:
Esophageal neoplasms;
Biopsy;
Papillomavirus,human;
Polymerase chain reaction
- From:
Chinese Journal of Experimental and Clinical Virology
2011;25(1):39-41
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prevalence of human papillomavirus (HPV), particularly of high-risk HPV in biopsy tissue specimens of esophageal carcinomas in Linzhou city. Methods General nested primer sets were used to detected the whole HPV genotypes, following by HPV16 and 18 type specific PCR for the HPV16 and 18 detection respectively. Results All 18 biopsy samples were HPV positive, and HPV 16 was detected in 13 of the 18 samples, HPV 18 was detected in 4 of the 18 samples. Conclusion The high rate of HPV in the esophageal carcinoma samples suggested that HPV infection may be an important etiologic factor in the development of esophageal cancer in Linzhou city.
