Study of human papillomavirus in small cell neuroendocrine carcinoma of the uterine cervix.
- Author:
Li-hua BIAN
1
;
Xiao-li WANG
;
Yi-fan GUO
;
Xiao-zhou WU
;
Lei SONG
;
Hong-tu LIU
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Base Sequence; Carcinoma, Neuroendocrine; virology; Carcinoma, Small Cell; virology; Female; Human papillomavirus 18; genetics; isolation & purification; Humans; Molecular Sequence Data; Polymerase Chain Reaction; Uterine Cervical Neoplasms; virology
- From: Chinese Journal of Experimental and Clinical Virology 2011;25(1):63-65
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the infection of the high risk human papillomavirus (HPV) in the specimen of the small cell neuroendocrine carcinoma of the uterine cervix (SCNEC).
METHODSWe extracted the nucleic acids in the formalin-fixed and paraffin-embedded specimen from a 33-year-old patient diagnosed as small cell neuroendocrine carcinoma of uterine cervix and detected the HPV genotype with the nested PCR.
RESULTSWe identified HPV18, a high-risk genotype, in the specimen.
CONCLUSIONThe HPV detection with the nested PCR was available for identification of the HPV genotype(s) in the paraffin-embedded specimens of small cell neuroendocrine carcinoma of the uterine cervix with a high accuracy and sensitivity.
