Study of human papillomavirus in small cell neuroendocrine carcinoma of the uterine cervix
10.3760/cma.j.issn.1003-9279.2011.01.021
- VernacularTitle:宫颈小细胞神经内分泌癌中人乳头瘤病毒的研究
- Author:
Li-Hua BIAN
1
;
Xiao-Li WANG
;
YI-Fan GUO
;
Xiao-Zhou WU
;
Lei SONG
;
Hong-Tu LIU
Author Information
1. 解放军总医院妇产科
- Keywords:
Cervix neoplasms;
Carcinoma,small cell;
Carcinoma,neuroendocrine;
Papillomavirus,human;
Polymerase chain reaction
- From:
Chinese Journal of Experimental and Clinical Virology
2011;25(1):63-65
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the infection of the high risk human papillomavirus (HPV) in the specimen of the small cell neuroendocrine carcinoma of the uterine cervix (SCNEC). Methods We extracted the nucleic acids in the formalin-fixed and paraffin-embedded specimen from a 33-year-old patient diagnosed as small cell neuroendocrine carcinoma of uterine cervix and detected the HPV genotype with the nested PCR. Results We identified HPV18, a high-risk genotype, in the specimen. Conclusion The HPV detection with the nested PCR was available for identification of the HPV genotype(s) in the paraffinembedded specimens of small cell neuroendocrine carcinoma of the uterine cervix with a high accuracy and sensitivity.
